December 30, 2005
A new and much discussed analysis, has shown that nearly every other cancer case can be prevented by D vitamin, if everyone is getting the suffient dosage, which almost no one is.
It has now been proven that the frequency of cancer can be reduced dramatically by increasing the population’s vitamin D intake.
This is the claim of the American researcher Cedric Garland, who is a professor of epidemiology at the University of Southern California, San Diego. He is behind the largest analysis of vitamin D research and cancer to date. 63 studies from 1962-2004 were analysed.
As a whole they strongly indicate that if the population’s intake of vitamin D is set up to 1,000 units per day, the frequency of colon cancer would be halved while the number of breast cancers and ovarian cancers would be reduced by a third. The 1,000 units of vitamin D (25 micrograms) would be, with certainty, without side effects. This is the same as five times the normally recommended dose, which only few receive.
Garland, who has studied vitamin D for 25 years, is very certain of his results. In a statement given to the BBC and The Independent he declared that there is now such an overwhelming amount of indications from the best observational studies, that governmental action is warranted.
It is worth noticing that these internationally respected media concerns both came with detailed reports, which also were followed by a leading editorial in The Independent. The study itself was published in the February 2006 issue of the American Journal of Public Health. The results were also published beforehand online in an extensive statement on the university’s (UCSD) official homepage.
Garlands interest for vitamin D was awakened when he noticed in the 1980’s that the risk of colon cancer and breast cancer in the northern United States was double that of the risk in the Southern states. He and others started a 12 year study, which lead to a hypothesis that the reason behind this phenomenon is sunlight’s ability to create vitamin D in the skin. This theory has subsequently been tested in many ways. It also fits with the increased cancer frequency in cities, when air pollution containing sulphur dioxide blocks the vitamin D producing short ultraviolet solar radiation.
This also fits with the diet and cancer studies on workers in Chicago and with the low frequency of breast cancer in Japan, where though there is little sunlight, the diet is largely fish based. Fatty fish are just about the only regular source of vitamin D outside of the summer months in Japan, Chicago, and Northern Europe. Additionally, the theory fits well with the fact that the many people, who for genetic reasons utilize vitamin D poorly, are strongly overrepresented among those who suffer cancers of the colon, breast, prostate, and more.
More and more indications
The faithful subscribers to this newsletter may remember our accounts of the studies of the last year which have shown that women with low vitamin D status have much more frequently lumps in their breasts than others. This is a relationship which fits with a higher risk of cancer.
They may also remember that an American (as well as a large Norwegian) study showed that the possibility of beating many cancer forms is best when the cancer is found during the summer, when vitamin D status is highest.
This indicates that the vitamin not only prevents cancer, but also inhibits cancer growth. Concordantly with Garland’s claim, African Americans have a lower chance of recovery form breast cancer than Anglo Saxon individuals. This may be due to a reduced vitamin D status brought on by the reduced ability to absorb vitamin D which comes with dark skin colour.
These results and others are strengthen by animal studies where it has been proven that vitamin D promotes cell death in abnormal cells in the process called apoptosis and has a general dampening effect on cell growth. This last principle is utilized by psoriasis salves, which contain a vitamin D – like substance which inhibits the overwhelming growth and lack of cell maturation which characterises this skin disease.
The optimal daily vitamin D dose, especially during the winter months between October and May, is according to Garland about 1,000 units (or 25 micrograms) per day. This recommendation is based on a study from October 2005. The 1,000 units lead to a concentration of the vitamin D precursor 25-OH-vitamin D of about 80 nmol/l (nanomol per litre), which Garland found to lead to the lowest risk of colon cancer.
Much also indicates that Garland is correct that vitamin D supplements could save thousands of lives. If this is the case, than any media claim that we get superfluous vitamins is contrary to public health.
By: Vitality Council
1. Garland CF et al. The Role of Vitamin D in Cancer Prevention. Am J Public Health. 2006;96(2):9-18. 2005 Dec 27; [Epub ahead of print].
2. Gorham ED et al. Vitamin D and prevention of colorectal cancer. J Steroid Biochem Mol Biol. 2005 Oct;97(1-2):179-94. Epub 2005 Oct 19.
3. Garland CF et al. Serum 25-hydroxyvitamin D and colon cancer: eight-year prospective study. Lancet. 1989 Nov 18;2(8673):1176-8.
4. Jeremy Laurance, Health Editor. Revealed: the pill that prevents cancer. The Independent 28.12.05.